Sodium Monofluorophosphate

Pharma / Cosmetic Grade (Toothpaste Grade) — Bulk supply across India & International Markets

What is Sodium Monofluorophosphate?

Sodium Monofluorophosphate (SMFP) is a white crystalline powder that serves as one of the primary sources of fluoride used in oral care products, particularly toothpaste. Unlike sodium fluoride, SMFP releases fluoride ions gradually through enzymatic hydrolysis in the mouth, and is valued for its compatibility with calcium-containing abrasive systems commonly used in toothpaste formulations, where it does not react with calcium to form insoluble compounds the way sodium fluoride can.

Polychem Industries supplies Sodium Monofluorophosphate in pharma and cosmetic grade (toothpaste grade) to oral care product manufacturers and dental product formulators across India and internationally. Its proven anti-caries efficacy, combined with excellent compatibility with common toothpaste abrasive systems, has made it one of the most widely used fluoride sources in the global oral care industry for decades.

Available Grades

GradeFormPurityStandardApplications
Pharma / Cosmetic Grade (Toothpaste Grade)White crystalline powder98%+ (Pharma / Cosmetic Grade)IP / BP / CosmeticToothpaste, mouthwash, dental care products

Applications & Uses

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Toothpaste Formulations

The primary and most significant application. SMFP is used as the active fluoride ingredient in a large proportion of toothpaste formulations worldwide, providing anti-caries (cavity prevention) benefits through its gradual fluoride release mechanism.

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Mouthwash & Oral Rinses

Used in certain fluoride mouthwash and oral rinse formulations as an alternative fluoride source, providing similar anti-caries benefits to other fluoride compounds used in oral care rinse products.

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Dental Gels & Professional Care Products

Used in professional dental care products including fluoride gels and treatments applied in dental clinics or recommended for at-home use as part of comprehensive caries prevention programmes.

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Children's Oral Care Products

Used in toothpaste formulations specifically designed for children, often at adjusted fluoride concentrations appropriate for paediatric use, taking advantage of SMFP's well-established safety profile in oral care applications.

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Calcium-Compatible Formulations

Particularly valued in toothpaste formulations using calcium carbonate or other calcium-based abrasive systems, where SMFP's compatibility avoids the calcium-fluoride interaction issues that can occur with sodium fluoride in such formulations.

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Dental Research & Diagnostic Applications

Used in certain dental research applications studying fluoride uptake and anti-caries mechanisms, given its well-characterised release kinetics in oral environments.

Technical Specifications

Sodium Monofluorophosphate — Key Properties

Chemical FormulaNa2PO3F
CAS Number10163-15-3
Molecular Weight143.95 g/mol
AppearanceWhite crystalline powder
Purity98%+ (Pharma / Cosmetic Grade)
Melting Point>625°C (decomposes)
Density / Bulk DensityBulk density: 0.9–1.1 g/cm3
pH6.5 – 9.0 (1% solution)
Packaging Available25 kg bags
StorageStore in cool, dry place away from moisture. Stable under normal storage conditions. Shelf life 24 months.

Why Source Sodium Monofluorophosphate from Polychem Industries?

  • Pharma / Cosmetic Grade (Toothpaste Grade) with full quality documentation
  • Certificate of Analysis available on request
  • Excellent compatibility with calcium-based toothpaste abrasive systems
  • Reliable bulk supply for oral care and dental product manufacturers
  • Competitive pricing with consistent year-round availability
  • Export documentation experience for international shipments

Frequently Asked Questions

Why is SMFP used instead of Sodium Fluoride in some toothpaste formulations?
SMFP is particularly valued in toothpaste formulations that use calcium carbonate or other calcium-based abrasive systems, because unlike sodium fluoride, SMFP does not readily react with calcium ions to form insoluble calcium fluoride, which would reduce the bioavailable fluoride in the formulation. This compatibility makes SMFP the preferred fluoride source for calcium-based toothpaste formulations.
How does Sodium Monofluorophosphate release fluoride in the mouth?
SMFP requires enzymatic hydrolysis (breakdown by enzymes present in saliva and dental plaque) to release free fluoride ions, which then become available to interact with tooth enamel for anti-caries benefit. This is different from sodium fluoride, which releases fluoride ions immediately upon dissolution, giving SMFP a somewhat different release profile and mechanism of action.
Is Sodium Monofluorophosphate safe for use in oral care products?
Yes — SMFP has an extensive history of safe use in toothpaste and oral care products spanning many decades, supported by substantial clinical research demonstrating its anti-caries efficacy and safety profile. It is approved for use in oral care products by regulatory authorities worldwide, including in India under applicable cosmetic and pharmaceutical regulations.
Do you export Sodium Monofluorophosphate outside India?
Yes. We export to Bangladesh, Sri Lanka, Nepal, Bhutan, and South Africa with full export documentation. Contact us for export pricing and lead times.

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